House vacation rentals in South Carolina

Find and book unique houses on Airbnb

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Popular amenities for South Carolina house rentals

Pet-friendly house rentals

Guest favorite
A spacious, fenced backyard features lush green grass and a canopy of trees providing partial shade. The area is free of obstacles, allowing for various activities. The yard is well-maintained, ensuring a comfortable environment for pets and guests alike.
Home in Charleston
4.97 out of 5 average rating, 193 reviews

Charleston Charmed Cottage - 3 bd/2ba

CindaRating, 5 stars2 weeks ago
This was the perfect nest for us as we attended the Charleston WTA tournament. The quiet neighborhood of Avondale offers wonderful restaurants, shops and our favorite coffee place, Highfalutin. We loved the comfy decor, high end bedding and the endless accouterments in the kitchen and bathrooms. The star of the show was the awesome screened porch where we spent mornings with our tea, coffee and breakfast. Ingrid the host was the best with her check ins and great communication. We loved our week here!
Guest favorite
The kitchen features modern white cabinetry and stainless steel appliances, with a streamlined design and ample natural light. A hanging rack displays red cookware above a dark kitchen island, while yellow decorative pillows are arranged on a brown sofa nearby.
Home in North Charleston
4.85 out of 5 average rating, 133 reviews

3bd, 3 Private Baths in Park Circle

PamRating, 5 stars2 months ago
It was definitely in a sketchy area but when we arrived to the particular neighborhood it was a cool spot with lots of personality.
Guest favorite
A welcoming porch area features several rocking chairs made from weathered wood, paired with colorful cushions. A front row of chairs faces large sliding glass doors, reflecting light from the outside. Decor accents include a blue throw pillow and glimpses of coastal decor nearby.
Home in Pawleys Island
4.93 out of 5 average rating, 134 reviews

Pawleys Island-2nd row-faces ocean:June-Sept-Sa-Sa

ElizabethRating, 5 stars5 days ago
Clean and well stocked house, although we were in town for a wedding so did not spend much time in the home or going to the beach. Donna was kind and responsive in communicating. Front door a bit difficult to lock/unc lock so we used the back door to come and go. Linens and towels were clean and well stocked. House is older, so a few things like the shower/tubs are a bit older and the water pressure is so so, but overall the layout was great for our group and we enjoyed our stay.
Top guest favorite
A well-appointed bedroom features a stylish metal bed frame with layered bedding and decorative pillows. Natural light filters through white blinds, illuminating the space. A bedside table with a lamp is positioned beside the bed, while a laundry basket and dresser are visible in the foreground.
Home in Walterboro
5 out of 5 average rating, 140 reviews

The Cozy Casa

CyliaRating, 5 stars1 week ago
An awesome place to stay whether you’re traveling by yourself or with the fam bam. The most stocked Airbnb house I ever stayed at. Every detail makes it very welcoming and comfortable. Minutes from the freeway, Crackle Barrel, and a gas station. Will definitely book again in the future.
Top guest favorite
A bright living area features a cozy seating arrangement with two plush armchairs and a sectional sofa. A modern coffee table sits in the center, while a large wall-mounted television is positioned above an elegant fireplace. Natural light filters through large windows adorned with light curtains.
Home in Rembert
4.97 out of 5 average rating, 187 reviews

New Home! Only 15 min to Shaw/Sumter. Dog friendly

AngelaRating, 5 stars5 days ago
We stayed during Boykin Nationals and its was a great location for us. The house was clean and the space worked well for our family and pet. The small fenced in backyard made letting the dog out easy and the host was very easy to get a hold of and work with. We will definitely be coming back!
Guest favorite
A backyard space features a mix of natural grass and artificial turf, with shaded areas provided by oak trees. Several patio chairs surround a firepit, and a wooden deck extends for outdoor gatherings. Cornhole games and seating options create inviting spots for relaxation.
Home in Mount Pleasant
4.88 out of 5 average rating, 237 reviews

“Shadow Oaks”: Home Away From Home

GabrieleRating, 5 stars3 weeks ago
The owners were very responsive to any questions or concerns we had. I highly recommend this place due to the location to everything to do in Charleston and access to beaches, restaurants and shopping.
Guest favorite
A two-story house with a covered front porch and a charming brick chimney. The exterior features light beige siding and dark green shutters. A welcoming entrance is highlighted by a solid door and decorative window, while the upstairs balcony provides additional outdoor space.
Home in North Myrtle Beach
4.88 out of 5 average rating, 147 reviews

Dogs dogs and more dogs all pets welcome

ChrisRating, 5 stars2 weeks ago
We loved staying here, it felt like a home away from home. Short walk to the beach / ocean. Accessible to stores and restaurants. Host was wonderful. Highly recommended and would come back again! Thanks for having us.
Guest favorite
A simple brick home is surrounded by trees, featuring a well-maintained lawn. A driveway leads to a parked dark SUV in front of the house. The front porch is accessible, with a door centered between two sets of windows, framed by black shutters.
Home in Ladson
4.82 out of 5 average rating, 126 reviews

Simple Pet Friendly Home

MichelleRating, 5 stars2 weeks ago
Stayed for 4 nights with our dog and two cats. Home was perfect for our needs. While not in an area with a lot of entertainment or many restaurants, it is in close proximity to areas with lots of these things. House is clean and cozy. Julia is a great host - not intrusive but very responsive, and very flexible. Stay was worth every penny we paid! Would highly recommend to anyone needing a pet friendly place to stay!

House rentals with a pool

Guest favorite
A spacious living area is furnished with two white sofas and two armchairs, each adorned with teal cushions. A circular coffee table is centered on a patterned area rug, and artwork hangs on the dark walls. Natural light floods the room through large windows.
Home in Charleston
4.97 out of 5 average rating, 238 reviews

2500SF Downtown 1849 home w/ pool!

MatthewRating, 5 stars3 months ago
Great place, great host. Franks concern for everything really shows in his unit. Even putting up some Christmas lights outside before our arrival. Great walkable area. And 4 places close by - Vern’s, Chubby Fish, Island Provisions and D'Allesandro's. Great food all at different levels. And 1 street over from King St so close enough to walk but far enough away that you don’t get the craziness. So - perfect spot. You’ll enjoy Franks place.
Guest favorite
An open-concept living area features high, exposed wooden beams overhead. A spacious gray sofa sits across from a glass coffee table, surrounded by casual seating. An island bar with high stools separates the living space from the sleek kitchen, illuminated by natural light streaming through multiple windows.
Home in Charleston
4.9 out of 5 average rating, 207 reviews

Boutique Home & Resort Pool ‘The Kiawah’

MargaretRating, 5 stars2 weeks ago
Beautiful and clean home with all of the amenities we would have needed, including a beautiful pool. Host was responsive and made for a lovely stay!
Superhost
A staircase with wooden steps leads to an upper level, accompanied by a light blue wall. The open-concept area features a kitchen with dark wood cabinetry, a breakfast bar with several stools, and a cozy seating arrangement. Natural light brightens the space.
Home in Myrtle Beach
4.81 out of 5 average rating, 128 reviews

Ocean Breeze~Amazing Location~Steps to the Beach!

CharlesRating, 5 stars1 month ago
She was exactly what you would expect from the perfect hostess. I had a wonderful stay and I would love to do the same in the near future. Thank you for being prompt on responding to our messages and making our little vacay awesome!
Guest favorite
Home in Kiawah Island
4.83 out of 5 average rating, 132 reviews

Kiawah Island Home w/ Pool - 4 bedroom /4 bath

JohnRating, 5 stars4 months ago
Jayne’s home was fantastic. It was spacious, inviting, and had all of the amenities you could ask for. While we didn’t get a chance to use the pool because of the very cold weather, the pool looked absolutely incredible and would be perfect on a warmer day. The location of the home was also very close to the beach. I could not imagine a more relaxing environment in which to spend time in Kiawah. I hope to return in the future!
Top guest favorite
A fenced backyard features a private saltwater pool surrounded by sun loungers. An umbrella provides shade beside the pool, while the patio area showcases a gas grill. The exterior of the house is stylishly designed with large windows providing a bright, inviting environment.
Home in North Charleston
4.98 out of 5 average rating, 137 reviews

Modern Family Home| Private Pool| Games| Huge Yard

KathyRating, 5 stars1 week ago
This place was perfect for our needs! The host was extremely friendly and helpful. The house was exactly as described and super clean and well stocked! The bed was very comfortable and the sheets were the nicest sheets to sleep on!. Overall extremely satisfied with our experience.
Guest favorite
Home in Ridgeway
4.91 out of 5 average rating, 46 reviews

6 Bedroom Lake House with a heated pool

BradRating, 5 stars4 days ago
Clean, plenty of entertainment, minimal cleaning request for check out. The house is stunning and so is the view of the lake. It is BEAUTIFUL. I would absolutely stay here again.
Superhost
A welcoming entrance features a brick facade and a solid white door, framed by two symmetrical windows with dark shutters. Lush greenery lines the steps leading up to the porch, creating a sense of privacy and warmth.
Home in Greenville
4.77 out of 5 average rating, 48 reviews

3br Private Oasis with Huge Pool and Deck/Hot Tub!

KaleyRating, 5 stars1 week ago
Dan’s place was great- gorgeous pool, amazing setup, clean, close to downtown, wonderful amenities, etc. I would love to stay here again - highly recommend!
Top guest favorite
A spacious backyard features an in-ground swimming pool surrounded by well-maintained grass and mature trees. A patio area with shade is visible, providing a serene setting for relaxation. The pool area is enclosed by a wooden fence, ensuring privacy.
Home in Fountain Inn
4.96 out of 5 average rating, 113 reviews

Spacious 3 BR house with private backyard oasis.

CindyRating, 5 stars1 month ago
Another great stay at Jesses. We were able to explore downtown fountain Inn with its restaurants and boutiques. The house is near the Swamp River Trail so that you can walk your dog , the house has comfortable beds and is outfit fitted with all the essentials you need for a great stay

Weekly house rentals

Guest favorite
The front exterior of a single-story home is presented, featuring a wide, grassy lawn and a covered porch. Positioned on the porch are several rocking and Adirondack chairs, creating a welcoming outdoor seating area. Trees line the property, and a golf cart is visible on the driveway.
Home in Murrells Inlet
5 out of 5 average rating, 12 reviews

Sunnyside Southern Charm

LeslieRating, 5 stars2 months ago
Rebecca's place was exactly as described and fit our short get away from the snow weekend. very close to several great seafood options. Rebecca was proactive and provided extra clear directions for check in and check out and was very responsive to any questions. I would highly recommend.
Guest favorite
A modern two-story house is shown with a covered porch and a light blue exterior. It is elevated on stilts, with a parking area underneath. Several windows are visible, allowing natural light to brighten the space while nearby trees provide shade.
Home in Myrtle Beach
5 out of 5 average rating, 62 reviews

Ocean Lakes - House

RebekahRating, 5 stars3 weeks ago
We really enjoyed our stay here. Before we arrived Charles had already contacted me, and sent all of the details. The house was real nice and clean upon arrival. My family will be returning in the future.
Superhost
Home in Myrtle Beach
4.85 out of 5 average rating, 39 reviews

OceanLakes! 2 Min Walk to Beach WaterPark WIFI

JamieRating, 5 stars6 months ago
The house was great and close to the beach. We had a great time and enjoyed all the amenities.
Superhost
The exterior of the cottage features a light blue facade with a welcoming turquoise door. Two adirondack chairs sit on the porch, adorned with colorful cushions. Windows with white frames allow natural light to brighten the space, surrounded by lush green grass.
Home in Myrtle Beach
4.73 out of 5 average rating, 78 reviews

Beach Cottage 1.5 Blks to Ocean & Blvd

FrankieRating, 5 stars7 months ago
Definitely enjoyed our stay at this property. Very clean and comfortable accommodations; most of all, very walkable, everything is only a block away. For sure would stay here again.
Superhost
A spacious living area is highlighted by comfortable seating, including a blue sofa with striped and red accent pillows. A glass coffee table sits in the center, with a fireplace and wall-mounted TV located nearby. Natural light fills the room through large windows.
Home in Isle of Palms
4.78 out of 5 average rating, 9 reviews

Amazing Island Home, Pool, Close to the Beach!

MichaelRating, 5 stars7 months ago
We had an amazing week with our three adult kids and their significant others! The home was beautiful! Comfy, clean, crisp ... everything we had hoped for and more! We were able to relax (plenty of comfortable space) and come together and enjoy our time together making meals, playing games, and watching movies. The location was excellent. Close to beach and town, yet quiet and private nestled in a beautiful neighborhood. Many memories were made with the family. We have already passed along our experince to interested friends and hope to have our family return again in the future.
Top guest favorite
The exterior of the house is showcased, featuring a single-story structure with a welcoming entrance. Lush green grass surrounds the home, with neatly trimmed hedges and plants. Trees in the background provide shade, and a fenced area adds privacy to the space.
Home in Charleston
4.96 out of 5 average rating, 179 reviews

Renovated - 3 Bed Home - 10 Minutes to Downtown!

JoyRating, 5 stars1 week ago
Great place to stay. Location is close to folly beach, close to Charleston and Mount pleasant, and James island was cute too. House was clean and nice. Would stay here again.
Superhost
A sunbeam filters through the trees, illuminating the entrance to a neighborhood with manicured hedges and palm trees. A street sign directs to 'Cabbage Court,' while a multi-story building displays a light grey exterior, blending with the natural surroundings.
Home in Hilton Head Island
5 out of 5 average rating, 3 reviews

Singleton beach-off season bookings

RuthRating, 5 stars10 months ago
We loved the home it was lovely. In my opinion the distance to the beach was an inconvenience. It’s a good walk for families with little kids or older retired adults. The golf cart was not accessible on one of the days and we didn’t get any communication about the situation until we were already at the beach. Driving was an option but even then the distance was long for my parents who are 80+. We still made memories and had a good time. The house was beautiful and very clean. Big enough for everyone to have their own space. My grandchildren loved the bunk beds 3-4 years of age. The hostess was wonderful. She was willing to help if needed.
Top guest favorite
A welcoming front porch is presented with comfortable seating and decorative cushions. A vibrant blue door acts as a focal point, framed by landscaping that includes planters and blooms. The space is shaded by a covered roof, creating an inviting area for relaxation.
Home in Port Royal
4.95 out of 5 average rating, 106 reviews

Sea Islander - GREAT vacation getaway!

Taylor KatherineRating, 5 stars1 month ago
We loved staying here. It was a last minute booking and we were desperate to find a place because of a prior booking falling through. We felt right at home right away. It’s walking distance to a delicious coffee shop/cafe & Spanish Moss Trail. We will definitely be recommending to visiting family members in the future!!

Destinations to explore