House vacation rentals in South Carolina

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Top-rated house rentals in South Carolina

Guests agree: these houses are highly rated for location, cleanliness, and more.

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Guest favorite

Home in Saint Helena Island

4.98 out of 5 average rating, 124 reviews

The Tidewatch: Beachfront Retreat on Harbor Island

Enjoy the ultimate beach vacation at the Tidewatch! Located directly on the sand with spectacular ocean views. Relax on the home's wrap-around porches while spotting dolphins or take a dip in the ocean right outside your front door. Located within the private, gated community of Harbor Island, a barrier island near Beaufort, SC with easy access to Charleston, Savannah, and Hilton Head. Guests have access to Harbor Islands' miles of sandy beaches, resort style pools, and recreation facilities.

Guest favorite

Home in Westminster

4.93 out of 5 average rating, 269 reviews

Waterfall Views, Lake Hartwell, Highland Architect

Come and enjoy nature with 100+ acres to roam. Paths for long walks. Architect James Fox designed this cliffside home overlooking a beautiful waterfall. Feel like you are in the trees, in an area much as it was when inhabited by Cherokee Indians. Stream feeds into Lake Hartwell. In the summer months on the weekends and holidays kayaks, jet skis and small boats visit the falls. This property is in the foothills of the Appalachian Mountains. Please respect our pet policy, only service animals.

Guest favorite

Home in Chappells

4.95 out of 5 average rating, 155 reviews

Greenwood Lake Front, FirePit, Outside Kitch, Dock

Our place is unlike any other on the lake! The home is fully stocked and includes kayaks, pedal boat and lilly pad for your enjoyment. We have a dock and firepit. You will have no need to go anywhere else while you are here, as Camp Q has so many things to offer. The outside kitchen has 2 grills and a fridge. You’ll love my place because of the outdoors space, and the ambiance. My place is good for couples, solo adventurers, families (with kids), big groups, and furry friends (pets).

Guest favorite

Home in Lexington

4.97 out of 5 average rating, 147 reviews

Lakefront home on Lake Murray with private dock

Lakefront home on Lake Murray in Lexington, SC on over 1/2 an acre, 166 feet of waterfront with deep water, private dock, and entertainment space- perfect for an unforgettable vacation or weekend. Entire home for rent-4BR, 3 Bath +2 half baths, 2 sofa sleepers, sleeps 12. Breathtaking kitchen & large living space, perfect for the entire family. 2 single person kayaks, outdoor grill, 65 inch and 55 inch TV, washer/dryer, and fast wifi. Master suite with a lavish bathroom and soaking tub.

Guest favorite

Home in Greenwood

5 out of 5 average rating, 110 reviews

The Little White House

Kick back and relax in our BRAND NEW guest house. We have put a lot of thought and effort into our space for you to have a comfortable stay. Enjoy a country living feel while being just minutes from shopping, restaurants, and the hospital. The host also live behind the property should you need anything. No pets. No smoking. This space is for paying guest only. No parties! We also have a 2nd listing in Greenwood- The Cottage @ Hill & Dale. *OWNER IS A LICENSED REAL ESTATE AGENT.

Guest favorite

Home in Saint Helena Island

5 out of 5 average rating, 103 reviews

Peaceful treehouse with spectacular views on Fripp

Our cozy getaway on Fripp Island near the beach is a perfect retreat to unwind and relax. It provides a tranquil escape from the noise and chaos of everyday life, allowing you to enjoy the serene beauty of Fripp Island. Spend your days lounging in the hammock taking in the spectacular saltwater marsh views, sunbathing on the beach, exploring the island on the bicycles, or just sitting in the lanai with a book, our private oasis in the trees can cater to your needs.

Guest favorite

Home in Greenville

4.99 out of 5 average rating, 164 reviews

Cozy Treehouse

Situated at the back of a wooded 2 acre lot, only 10 minutes from downtown Greenville, this is a little oasis in the city! While most treehouses take you on a "roughing it" adventure, Cozy Treehouse is the glamping version of treehouses, boasting 9' ceilings, 1.5 baths, 3 LED TV's and many outdoor living options. If you are looking for a unique getaway just minutes from one of the top growing cities in the south, Cozy Treehouse is the perfect destination for you.

Guest favorite

Home in Prosperity

4.99 out of 5 average rating, 152 reviews

Anchors Aweigh

You'll enjoy this small cabin located less than 2 miles from Dreher Island State Recreation Area. The views from the living area and kitchen are breath-taking. You can sit on the dock & watch the sun set or take your boat out just a few hundred yards to watch the sun rise. This location is great for swimming & a dock is available so you can bring your boat. There is also great fishing from the dock and on a boat. This will provide an unforgettable vacation!

Guest favorite

Home in Pawleys Island

4.93 out of 5 average rating, 138 reviews

3BR 2 Bath Remodeled House Close to Beach & Golf

Newly remodeled spacious 3 bedroom 2 bath house located in the classic Litchfield Country Club, just 5 minutes from Litchfield beach. The house includes a large kitchen that has everything you would need to cook a family meal. There is an enormous 2 car garage with a washer and dryer. Also included is 4 beach bike cruisers which can be used to ride to Litchfield beach. The beds are new and comfortable. Restaurants, golf, and grocery stores are close by.

Guest favorite

Home in Folly Beach

4.86 out of 5 average rating, 156 reviews

Luxury Beach Front Pet Friendly

Located minutes from the Morris Island Light House, indulge in the epitome of seaside luxury at our beachfront vacation home, where every detail has been thoughtfully curated to ensure a perfect retreat. Located directly on Folly Beach's pristine shores, this 2023 to the studs renovated cottage seamlessly blends opulence with comfort, offering a harmonious escape for you, your loved ones, and even your four-legged friends.

Guest favorite

Home in Summerton

4.97 out of 5 average rating, 137 reviews

Luxurious Lakefront Log Home W/Pool & hot tub

Gorgeous luxury log home directly on the big waters of Lake Marion with fishing pier/boat dock, brand new salt water pool, hot tub and much more! This custom home boasts 3 large bedrooms and a loft, two large bathrooms with double sinks, one with claw foot soaker tub and separate water closet. Huge screened in back porch for dining and entertainment with custom 12' outdoor bar. This home is 6 minutes from I-95.

Guest favorite

Home in Abbeville

4.99 out of 5 average rating, 252 reviews

**Oak View**Peaceful**8 min to Erskine

If you are looking for a place to kick your shoes off and relax this is it! Whether its on the comfortable couches or on your own private deck watching the sunset and the cows grazing peacefully in the pasture. Everything has been updated from the new floors, paint, and new appliances and it's sparkling clean. the big bedroom has a king size bed and plenty of space to unpack and relax.