
House vacation rentals in Santo Domingo
Find and book unique houses on Airbnb
Top-rated house rentals in Santo Domingo
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Santo Domingo house rentals
House rentals with a pool

Steel-Loft - Whole house with sea-view terrace
We had a wonderful stay at this beautiful, modern, convenient house. Manuel was a truly great host - friendly, communicative, and prompt to respond to any issue. I really appreciated the detailed instructions on how to find the house and get inside. We loved the small plunge pool/ hot tub, as well as the roof terrace, and the location was great for walking to lots of restaurants and shops in the colonial zone. Thank you for a great stay in Santo Domingo!

villa yaya
The place is much more beautiful than what you can see in the photos.

PrivatePool - BBQ - Terrace - Excelent for Big Fam
A very nice place especially the pool area which has plenty of furniture for entertaining. Clean house in a secure area.

Casa Ozuna POOL & BBQ 1
Great place , Bryan very attentive !

AD featured slow life villa & scenic pool
This is a perfect location for a group. Each room is essentially an efficiency apartment with a small kitchen and bath. The history is evident and I love this part of the city. I recommend it highly. The pool however does not get much sun, but it’s charming and good for a dip!

Simply beautiful
Beautiful place and great location. You can go anywhere in 10-20 mins and airport is like 30 mins away

Spacious and cool house with a pool and patio
The host is very nice no complaints

• City Oasis • Luminous House nr Colonial Zone
Beautiful and huge house, fully equipped. Also fresh due to the high ceilings. Easy checkin and checkout. My family loved to hang out in the patio having coffee. The hosts were super responsive and attentive. Recommended!
House rentals with a hot tub

Luxury Morden house with Jacuzzi Zona Colonial.!
This apartment was amazing and the Jaccussi was the best part.! Beautiful roottop with ocean view well furnished.! Really love it.!

🛁JACUZZI🛁 ~🌈 My House RD#2 where you are a VIP guest •
The stay was amazing a relaxing home to stay in very comfortable and clean house quiet neighborhood definitely would recommend to anybody

Casa Grullon, an Oasis in the Colonial Zone
This stunning colonial gem transports you back in time while still offering all the modern comforts you could ask for. The attention to detail in the restoration is incredible—every corner of the property is filled with history, charm, and elegance. The tranquil courtyard and refreshing pool provided the perfect escape from the city’s energy, and the vintage luxury rooms made us feel like we were in a different era. It truly felt like stepping into a storybook. Our host was nothing short of amazing—so welcoming, attentive, and eager to make our stay perfect. Their hospitality added to the overall experience, making us feel at home while surrounded by the beauty of Zona Colonial. If you’re looking for a one-of-a-kind stay that blends history, comfort, and exceptional service, Casa Grullón is the place. We can’t wait to return! Thank you for everything!

HOUSE | 100% Private Jacuzzi Internet BBQ FreeNetflix
Excellent location, good service , the place was excellent and we would definitely stay again at another opportunity

Cozy & Beautiful City Center House with Jacuzzi
With all due respect to all other host. Johanne is the epitome of what a perfect host should be. The entire process was seamless. She met all of my questions and request with reason, kindness, efficiency and assurance. She is highly recommended by me and anyone considering this place… please know and understand that you will be taken care of. The location is amazing if you want peace and quiet and some privacy. You can uber anywhere meaningful in about 15-25 min. The home itself is beautiful, safe and very well accommodated.

Casa Aló:Private house with jacuzzi in the Capital
A perfect place to rest and spend time with the family

Entire house for rent, private, Picuzzi
great place great space ....love it

Mariu House
I was there on 3/29/25 with my partner, family and friends, it was a lot with too much, the place is wonderful, it is very nice, organized, everything clean and beautiful, a pleasant and quiet atmosphere, we were delighted, the people are very attentive as well as Marisol and Junior are a love, very attentive with us, the explanation of the stay was super clear, we were delighted! God bless you! And we'll be back soon, God willing🩷
Weekly house rentals

Luxury, Classy Private House In Santo Domingo
The house is located in a quiet and safe area. The host is very attentive and responds promptly, MARITZA is amazing, dedicated, friendly and makes you feel welcomed! We're definitely staying here again!!!

🔰The Best home🔰, Jacuzzi , WiFi + Netflix
I loved the place, everything was very nice and super easy to communicate with the host, I recommend it 100%. I can't wait to stay in this beautiful place again.

CASA DE RODRIGUEZ OFFICIAL APARTMENT
Everything excellent!!

Your own "Tropical Private Vacation Hotel"
This house is sooo beautiful! Very clean, very nice people! Good communication.

huge luxury two story private residential house
Had an exceptional stay at this place. The apartment is absolutely beautiful, tastefully decorated and attention to detail. The natural light that enters each room creates a warm and welcoming atmosphere. Additionally, the location is perfect, close to all the attractions. The host, incredibly welcoming and attentive, really made a difference. I would highly recommend this place to anyone looking for a place that is both beautiful and comfortable to stay! Thank you very much Leroy!

Casa Linda. Spacious family house in the best area.
The stay was awesome 👌🏾 I felt right at home. The neighborhood is safe and quiet. Nieveselis was so nice and friendly and was there when I needed anything.

DR 9BR Colonial Oceanview Place + Free Bonus
Can’t say enough about the quality of service, the responsiveness of the host and the attentiveness of the staff. Overall a fantastic stay from start to finish and the Airbnb and it’s crew were pivotal to our experience.

☀️Ginny's Guest House 1BD-☀️♥☕️☕️☺️
EXCELLENT, NOTHING TO complain about, the most comfortable I found, I recommend it for people who want a simple place without any luxury or the luxury of being surrounded by plants and birds in the morning. Thanks for everything.
Quick stats about house rentals in Santo Domingo
Total rentals
520 properties
Nightly prices starting at
ﺩ.ﺇ37 before taxes and fees
Total number of reviews
11K reviews
Family-friendly rentals
220 properties are a good fit for families
Pet-friendly rentals
130 properties allow pets
Rentals with a pool
110 properties have a pool
Destinations to explore
- Las Terrenas Vacation rentals
- Santiago de los Caballeros Vacation rentals
- Sosúa Vacation rentals
- Santo Domingo Este Vacation rentals
- Cabarete Vacation rentals
- La Romana Vacation rentals
- Juan Dolio Vacation rentals
- Bayahibe Vacation rentals
- Jarabacoa Vacation rentals
- Samana Vacation rentals
- San Juan Vacation rentals
- Punta Cana Vacation rentals
- Rentals with breakfast Santo Domingo
- Fitness-friendly rentals Santo Domingo
- Rentals with an accessible height bed Santo Domingo
- Rentals with a fireplace Santo Domingo
- Condo rentals Santo Domingo
- Rentals with a sauna Santo Domingo
- Serviced apartment rentals Santo Domingo
- Ski-in/ski-out rentals Santo Domingo
- Rentals with a hot tub Santo Domingo
- Rentals with a fire pit Santo Domingo
- Beachfront rentals Santo Domingo
- Rentals with lake access Santo Domingo
- Waterfront rentals Santo Domingo
- Loft rentals Santo Domingo
- Apartment rentals Santo Domingo
- Rentals with an EV charger Santo Domingo
- Family-friendly rentals Santo Domingo
- Mansion rentals Santo Domingo
- Rentals with outdoor seating Santo Domingo
- Rentals with beach access Santo Domingo
- Rentals with a washer and dryer Santo Domingo
- Rentals with a patio Santo Domingo
- Smoking-friendly rentals Santo Domingo
- Rentals with a home theater Santo Domingo
- Villa rentals Santo Domingo
- Rentals with pools Santo Domingo
- Pet-friendly rentals Santo Domingo
- Hotel rentals Santo Domingo
- Kid-friendly rentals Santo Domingo
- Guesthouse rentals Santo Domingo
- House rentals Distrito Nacional
- House rentals Dominican Republic
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom
- Things to do Santo Domingo
- Art and culture Santo Domingo
- Nature and outdoors Santo Domingo
- Things to do Distrito Nacional
- Nature and outdoors Distrito Nacional
- Art and culture Distrito Nacional
- Things to do Dominican Republic
- Food and drink Dominican Republic
- Nature and outdoors Dominican Republic
- Sightseeing Dominican Republic
- Tours Dominican Republic
- Art and culture Dominican Republic
- Entertainment Dominican Republic
- Sports activities Dominican Republic