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Vacation rentals in Santee

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Top-rated vacation rentals in Santee

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Home in Alpine

4.99 out of 5 average rating, 174 reviews

Fully Fenced Alpine Property with Guest House

Our guest house is located in the back of our personal property & kept private by fencing. Our property is fully fenced & guests have access in & out by using a keypad. We have laundry facilities, a queen size bed in the master bedroom, a sofa sleeper in the living room/kitchen area and a private patio with bbq. We occupy the main home on the property. We have 2 dogs on the property so other animals are not recommended at this location. Children swing set/tramploine not included with Airbnb.

Guesthouse in La Mesa

4.93 out of 5 average rating, 228 reviews

Fig Tree Bungalow

Enjoy your stay in San Diego in this newly renovated guesthouse. Centrally located about a mile from Hwy 8, Hwy 125, and the Grossmont Trolley Station & Transit Center. Only a 15-20 minute drive to downtown, the airport, the beaches, and most of San Diego's other popular tourist attractions. This cozy, two-story, detached unit is located behind my home, and has its own private entrance and partitioned yard for your enjoyment. There's plenty of street parking directly in front of the house.

Guest suite in Santee

4.95 out of 5 average rating, 295 reviews

Spacious 1 Bedroom unit w/ king bed & parking

Come relax in this bright & spacious 1 bedroom detached unit with private entrance. This room has a king bed, fireplace, full bathroom, table & chairs, mini fridge/freezer, microwave, closet ,dresser, Tv and beautiful mountain views. La Jolla Beaches, downtown San Diego, the Zoo, and Sea World are 25 minutes away. Santee Lakes is just a short drive away where you can enjoy fishing, paddle boating, splash park, biking and picnic area. Mission Gorge Trails is also located just 5 minutes away.

Home in La Mesa

4.86 out of 5 average rating, 206 reviews

Newer "Manor Studio"

Centrally located in San Diego County this brand new studio style unit has a private entrance, private patio area and street parking. Furnished with a queen size bed, love seat, full bathroom and kitchen area. One large drawer to accommodate personal items, and a wall rack to hang clothing. There is a smart TV with WiFi streaming capabilities and lots of USB plugs to charge your devices. On street parking in front of unit (no parking in driveway). No Pets allowed. No Hair Dying allowed.

Guesthouse in La Mesa

4.99 out of 5 average rating, 162 reviews

Stunning Guest House 15 min. from Zoo, Downtown

Stunning guest house that's 15 minutes to San Diego Zoo + downtown San Diego. The cottage is decorated with mid-century and one-of-a kind furniture in a comfy living space overlooking a gorgeous garden. Enjoy the the garden on your private deck, watch TV while relaxing in the handcrafted Nicaraguan rocker or 1950s Danish slipper chair. The cottage also has a comfy queen-sized bed and a full kitchen that's stocked with what you'd need. Oh, and all guests arrive to a homemade loaf of bread.

Guesthouse in El Cajon

4.96 out of 5 average rating, 104 reviews

Farmhouse Cottage Retreat with Mountain View’s

Welcome to the Farmhouse Studio Cottage located in the foothills of San Diego County. Formerly a horse and cattle ranch now transformed into a park like setting. See beautiful views as you drive down the tree lined inner roads of the property. Hear birds as you awake in the morning and an occasional rooster off in the distance. Get back to nature at this lovingly appointed studio hideaway. Close to Alpine and Sycuan Resort & Casino, Golf. Pet friendly, Pet fee of $60.00 per pet per stay.

Guesthouse in La Mesa

5 out of 5 average rating, 214 reviews

SDCannaBnB #1 *420 *parking *dog-friendly *hot tub

Welcome to SDCannaBnB - San Diego's premier cannabis-friendly rental! Our casita is newly remodeled with luxury ammenities. We proudly cater to the cannabis community and non-users alike. Our casita has HEPA air purifiers, is fully ventilated and receives deep cleanings between each guest. This ensures that every guest checks into a clean, fresh-smelling place that feels like home. Our casita is located in our quiet, fully fenced in backyard, close to San Diego's attractions

Rental unit in La Mesa

4.98 out of 5 average rating, 138 reviews

Lovely Hideaway Studio by Village-Private Patio

Enjoy the cool vibe at this unique rustic getaway tucked back on a tree-lined hill 5 minutes above City of La Mesa Village, 20 minutes from downtown San Diego. The studio is on the ground floor of our two-story house. We live on the 2nd floor, and the studio is it's own completely private space. 5 miles to San Diego State University; 16-20 miles to San Diego beaches; 10 miles to Downtown San Diego; 15 miles to Sea World San Diego; and 13 miles to the World Famous San Diego Zoo!

Guesthouse in El Cajon

4.98 out of 5 average rating, 206 reviews

Fletcher Hills - modern 1 BR.Easy, no step access.

** 48 hours between check-ins. Thorough cleaning and sanitizing.. Four night minimum stay. Dogs ONLY are welcomed on a case by case basis. They must be house trained and are not permitted on any furniture. If you instant book, you must contact me about your pet within 24 hours. Smoking is permitted in the outside areas - patio, gazebo, yard. Easy freeway access helps any commute to downtown and area attractions. Having your own vehicle is the best way to get around..

Rental unit in La Mesa

4.93 out of 5 average rating, 316 reviews

A Little Bit of Luxury in La Mesa! Private & Gated

Relax and stretch out on you king size bed or take a short stroll to La Mesa Village to take in the new shops, bars & restaurants. Enjoy your large lounge with flat screen TV & fireplace and while away the evening on your fully lit deck. The delights of downtown San Diego, beaches, zoo & airport are only a 15-20 minute drive away. Within walking distance to La Mesa Blvd Tolley stop. Apartment & parking for 1 vehicle is private & gated with plenty of on-street parking.

Barn in La Mesa

4.95 out of 5 average rating, 341 reviews

Enchanting Barn San Diego/La Mesa

DESCRIPTION: Relax and enjoy my converted Barn that is safe, cozy & comfortable. Barn has its own private entrance secured with a keyless entry lock. Sleep on a Cal King therapy foam bed, TV & Blu-ray player, CD stereo USB connection. Extra space has a large desk area. Barn has a private bathroom that includes a walk in shower. Guests provided with Freshly washed towels & linens. *I have a pet Nigerian Dwarf Goat who would love to meet you!

Home in El Cajon

4.97 out of 5 average rating, 116 reviews

Suite Charles Way: A Cozy Fletcher Hills Studio

This newly remodeled spacious studio retreat features a private courtyard with barbecue, kitchenette, a brand-new California King bed, and a reclining love seat with charging ports. Enjoy a relaxed cabana vibe, a charming neighborhood and treetop views with easy access to all your favorite San Diego destinations. Within minutes from Grossmont Sharp Hospital, Grossmont Center, the trolley and Grossmont College.

Vacation rentals for every style

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Popular amenities for Santee vacation rentals

Free parking on premises

Air conditioning

Stay near Santee's top sights

Cowles Mountain314 locals recommend

Santee Lakes Recreation Preserve27 locals recommend

Parkway Plaza Mall26 locals recommend

Santee Trolley Square23 locals recommend

Olive Garden Italian Restaurant16 locals recommend

Walmart13 locals recommend

Other great vacation rentals in Santee

Guesthouse in La Mesa

4.99 out of 5 average rating, 69 reviews

ino Mt. Helix Casita

Farm stay in El Cajon

5 out of 5 average rating, 45 reviews

Farmstay Gem near San Diego

Home in La Mesa

5 out of 5 average rating, 35 reviews

Shadow House November 14 & 15 discount!

Guesthouse in La Mesa

5 out of 5 average rating, 90 reviews

Private 1 BR Paradise retreat

Home in Santee

5 out of 5 average rating, 15 reviews

San Diego Santee Accessible 4 Bed w/ Pool

Rental unit in El Cajon

4.9 out of 5 average rating, 39 reviews

Quaint Apt with International decor

Guesthouse in Lakeside

4.84 out of 5 average rating, 56 reviews

Cute Tiny House in Lakeside

Home in El Cajon

5 out of 5 average rating, 43 reviews

Quiet Country Home

Quick stats about vacation rentals in Santee

Total rentals
110 properties
Total number of reviews
2.9K reviews
Family-friendly rentals
50 properties are a good fit for families
Pet-friendly rentals
30 properties allow pets
Rentals with a pool
50 properties have a pool
Rentals with dedicated workspaces
60 properties have a dedicated workspace

Frequently Asked Questions

Are there vacation rentals with a dedicated workspace in Santee?
Yes! Work meets play with ease at over 60 vacation rentals in Santee featuring dedicated workspaces. Stay connected and productive in your home away from home.
Are there Santee vacation rentals on Airbnb with pools?
Yes! Dive into the perfect getaway at one of over 50 vacation homes with pools in Santee, available on Airbnb. Make a splash and soak up the sun in style!
How much does it cost to stay in condo rentals in Santee?
Experience the best of Santee with our condo rentals, starting at about $60 per day, before taxes and fees. Embrace comfort and style while staying within your budget in your home away from home.
Do condo rentals in Santee have air conditioning?
Absolutely! We offer over 10 condo rentals with air conditioning in Santee. Enjoy a tailored experience with all the comforts you desire.
Are there pet-friendly vacation rentals in Santee?
Four-legged friends are welcome in Santee. Choose from more than 30 vacation rentals for guests traveling with pets.
Are there family-friendly vacation rentals in Santee?
Santee has more than 50 family-friendly stays. Amenities on the property may include high chairs, travel cribs, or strollers.
Do apartment rentals in Santee have wifi?
Absolutely! We offer over 10 apartment rentals with wifi in Santee. Enjoy a tailored experience with all the comforts you desire.
What are the most popular amenities for Apartment Rentals in Santee?
Enhance your stay in our Apartment Rentals with the most popular amenities: over 10 homes with wifi, over 10 homes with air conditioning, and more. Indulge in the ultimate retreat, tailored to your preferences.

Destinations to explore