
Villa vacation rentals in Santa Cruz de la Sierra
Find and book unique villas on Airbnb
Top-rated villa rentals in Santa Cruz de la Sierra
Guests agree: these villas are highly rated for location, cleanliness, and more.
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Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Santa Cruz de la Sierra villa rentals
Private villa rentals

Villa in Andrés Ibáñez Province
4.73 out of 5 average rating, 15 reviewsVilla with pool inside exclusive Polo Club
MelissaRating, 5 stars3 months ago
Super comfy and cozy place, very enjoyable!! Rafaella was kind and her father too!! The village indicated us everything right, I felt welcomed !
Guest favorite

Villa in Santa Cruz de la Sierra
5 out of 5 average rating, 25 reviewsGorgeous Villa (end of year Discounts!)
MarcoRating, 5 stars4 weeks ago
great host, wonderful place, kids loved the pool and work out area. coming back for sure!

Villa in Cotoca
4.86 out of 5 average rating, 7 reviewslake house in Cotoca
ManfredRating, 5 stars3 months ago
A very nice place to spend a few days with family or friends, with several options of activities within the place. It is only a few minutes away from shops and amenities in Cotoca, and still very private and quiet. Communication with the host is very quick and friendly. Recommended.
Superhost

Villa in Santa Cruz de la Sierra
4.94 out of 5 average rating, 17 reviewsUnique family retreat
SerenaRating, 5 stars1 month ago
Thank you very much, very nice place!!! We had a super quiet and pleasant time with family!! Thanks to the hosts, I was very quick and absolutely accessible!!! The place is beautiful and recommended if you are looking for relaxation and nature!!! Like I said all 10!!! Thank you Thank you thank you ….
Villa rentals with a pool

Villa in Andrés Ibáñez Province
4.73 out of 5 average rating, 15 reviewsVilla with pool inside exclusive Polo Club
MelissaRating, 5 stars3 months ago
Super comfy and cozy place, very enjoyable!! Rafaella was kind and her father too!! The village indicated us everything right, I felt welcomed !
Guest favorite

Villa in Santa Cruz de la Sierra
5 out of 5 average rating, 25 reviewsGorgeous Villa (end of year Discounts!)
MarcoRating, 5 stars4 weeks ago
great host, wonderful place, kids loved the pool and work out area. coming back for sure!

Villa in Cotoca
4.86 out of 5 average rating, 7 reviewslake house in Cotoca
ManfredRating, 5 stars3 months ago
A very nice place to spend a few days with family or friends, with several options of activities within the place. It is only a few minutes away from shops and amenities in Cotoca, and still very private and quiet. Communication with the host is very quick and friendly. Recommended.
Superhost

Villa in Santa Cruz de la Sierra
4.94 out of 5 average rating, 17 reviewsUnique family retreat
SerenaRating, 5 stars1 month ago
Thank you very much, very nice place!!! We had a super quiet and pleasant time with family!! Thanks to the hosts, I was very quick and absolutely accessible!!! The place is beautiful and recommended if you are looking for relaxation and nature!!! Like I said all 10!!! Thank you Thank you thank you ….
Destinations to explore
- Samaipata Vacation rentals
- Buena Vista Vacation rentals
- Montero Vacation rentals
- Porongo Vacation rentals
- Colinas del Urubó Vacation rentals
- Vallegrande Vacation rentals
- Cotoca Vacation rentals
- Yapacani Vacation rentals
- Portachuelo Vacation rentals
- La Guardia Vacation rentals
- El Torno Vacation rentals
- Cuevas Vacation rentals
- Rentals with a hot tub Santa Cruz de la Sierra
- Hotel rentals Santa Cruz de la Sierra
- Rentals with lake access Santa Cruz de la Sierra
- Serviced apartment rentals Santa Cruz de la Sierra
- House rentals Santa Cruz de la Sierra
- Rentals with a sauna Santa Cruz de la Sierra
- Condo rentals Santa Cruz de la Sierra
- Rentals with a fireplace Santa Cruz de la Sierra
- Rentals with pools Santa Cruz de la Sierra
- Family-friendly rentals Santa Cruz de la Sierra
- Smoking-friendly rentals Santa Cruz de la Sierra
- Rentals with a washer and dryer Santa Cruz de la Sierra
- Rentals with an EV charger Santa Cruz de la Sierra
- Rentals with breakfast Santa Cruz de la Sierra
- Fitness-friendly rentals Santa Cruz de la Sierra
- Pet-friendly rentals Santa Cruz de la Sierra
- Apartment rentals Santa Cruz de la Sierra
- Rentals with a fire pit Santa Cruz de la Sierra
- Rentals with a home theater Santa Cruz de la Sierra
- Beachfront rentals Santa Cruz de la Sierra
- Rentals with a patio Santa Cruz de la Sierra
- Cottage rentals Santa Cruz de la Sierra
- Rentals with outdoor seating Santa Cruz de la Sierra
- Kid-friendly rentals Santa Cruz de la Sierra
- Villa rentals Bolivia
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom