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Guesthouse vacation rentals in Nassau County

Find and book unique guesthouse rentals on Airbnb

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Popular amenities for Nassau County guesthouse rentals

Family-friendly guest house rentals

Guest favorite
Guesthouse in Jacksonville
4.73 out of 5 average rating, 448 reviews

Pool House-2 Bdr/1Ba Apt-Pool-Sleeps 5-Pets OK

RoseRating, 5 stars2 weeks ago
Great communication with the House pool was great for the kids easy to find
Guest favorite
Guesthouse in Jacksonville
4.95 out of 5 average rating, 149 reviews

The Funk House-A Retreat

PeteRating, 5 stars1 month ago
Leah is a super host and has so many great reviews for a reason! She’s very attentive to detail details and really wants her guest to have a welcoming comfortable enjoyable stay! Thank you for your hospitality leah I really enjoyed my time spent in your retreat house! And I enjoyed our conversation very much upon my departure. Thank you for taking the time.! 💜
Top guest favorite
Guesthouse in Jacksonville
5 out of 5 average rating, 29 reviews

Lovely Guesthouse in the Up-and-Coming Springfield

MariamRating, 5 stars5 months ago
Mateus and John are truly the most wonderful and kind hosts! I needed to check in a day early, and they graciously accommodated me at the last minute without any hesitation. Their home is SPOTLESS and beautifully decorated, featuring modern appliances. I appreciated having my privacy during my stay, while still knowing they were always quick to respond and available whenever I needed anything. I felt completely comfortable throughout my four-week stay!
Top guest favorite
Guesthouse in Fernandina Beach
4.9 out of 5 average rating, 231 reviews

Beachside cottage

ChristyRating, 5 stars1 week ago
Joy’s place was in such a beautiful location. I walked down to the beach every night and restaurants and amenities where’s far away. Her place was clean and cozy and had plenty of extras to use at the beach. Had a great time.

Guest house rentals with a patio

Superhost
Guesthouse in Jacksonville
4.8 out of 5 average rating, 49 reviews

La Casita

SherryRating, 5 stars1 day ago
I had a last minute visit to see my daughter, son in law and grandsons and needed a place quickly. Maria went above and beyond to accommodate my last minute reservation. She responded to my needs very quickly. Her place was so lovely and clean. I can't wait for my next visit and I will definitely be staying at her place each time. Thanks Maria you are a true gem!!!
Top guest favorite
Guesthouse in Jacksonville
5 out of 5 average rating, 29 reviews

Boone Park Studio

RachelRating, 5 stars1 week ago
It was a perfect little place for what we needed. Just got married and we enjoyed our first week together there very much!!
Top guest favorite
Guesthouse in Jacksonville
4.99 out of 5 average rating, 84 reviews

Farmhouse luxury, you'll never want to leave

CourtneyRating, 5 stars2 months ago
I had an amazing stay at Kristina’s place! From the moment I arrived, everything was perfect—check-in was seamless, and the space was spotless, cozy, and exactly as described. On top of that, it smelled incredible—I couldn’t get over how amazing it smelled! Kristina is a fantastic host, going above and beyond with thoughtful touches that made the stay even more special for me and my daughter. The location was fantastic, especially as a Jacksonville native. It truly felt like a home away from home, with a peacefulness that made the experience even better. One of the highlights of our stay was getting to feed the horses and pet the farm animals—it was such a cool and memorable experience! Kristina was incredibly responsive and helpful, always providing great recommendations and ensuring we had everything we needed. She went above and beyond in every way and was, without a doubt, the best Airbnb host I’ve ever had! I can’t wait to book again soon! All the best,
Top guest favorite
Guesthouse in Jacksonville
4.97 out of 5 average rating, 347 reviews

Henry’s Pad

SergeRating, 5 stars5 days ago
Thank you Jorge! House was spotless and very cozy. Felt like home.
Guest favorite
Guesthouse in Jacksonville
4.92 out of 5 average rating, 296 reviews

The Moody Loft (Murray Hill)

AleksandrRating, 5 stars1 week ago
Great price and great location. Cameron is a great communicator and his home is very easy to find. Highly recommend Dreamette!
Guest favorite
Guesthouse in Jacksonville
4.9 out of 5 average rating, 142 reviews

Charming Avondale Backhouse - King Bed!

JonathanRating, 5 stars2 weeks ago
The Knox family runs a solid Airbnb. They were on point—hospitable, quick to respond, and made sure everything was squared away. The place is in Avondale, a beautiful neighborhood in Jacksonville, and it’s in a prime spot—7 to 10 minutes from just about everything you’d need. No issues, no surprises, just a great stay. If I’m ever back in Jacksonville and they still own the place, I’ll be booking here again.
Top guest favorite
Guesthouse in Jacksonville
4.98 out of 5 average rating, 149 reviews

Stylish Bungalow Near Dining,Parks & Entertainment

DeannaRating, 5 stars1 week ago
Loved my stay! Excellent location and adorable vibes inside and out of the house. Such a great find - looking forward to staying again next time I’m in Jax.
Guest favorite
Guesthouse in Jacksonville
4.96 out of 5 average rating, 106 reviews

Spacious 2/1 in historic walkable neighborhood

ChristopherRating, 5 stars1 month ago
I honestly have no complaints… there is a lot of trees around the BNB and yet, I didn’t even see one bug… the communication was great as I called them when I needed help finding the home and was answered almost immediately. The area is also pretty quiet with multiple fast foods within a 10 min drive.

Guest house rentals with a washer and dryer

Top guest favorite
Guesthouse in Jacksonville
5 out of 5 average rating, 16 reviews

Bold City Bungalow

KylaRating, 5 stars5 months ago
My stay was amazing. The listing looks exactly as it’s shown, Kyle is very responsive and helpful about questions that I had, and as a non local I really appreciated the brochure on things to do in the area. 10/10 amazing experience
Top guest favorite
Guesthouse in Jacksonville
4.96 out of 5 average rating, 81 reviews

Private Studio Carriage House

vaunRating, 5 stars1 week ago
My daughter and I spent two nights at Steve's place. It was beautifully furnished and decorated. It was absolutely spotless and well-equipped. The location was fabulous- a block away from charming shops and restaurants. Both days my daughter and I enjoyed the short walk to get a bite to eat and check out the shops. Steve and his wife were very friendly and gracious. I would definitely stay here again and highly recommend this adorable studio apartment.
Guest favorite
Guesthouse in Jacksonville
4.9 out of 5 average rating, 283 reviews

Downtown Jacksonville Historic District

AnayahRating, 5 stars1 month ago
Great hosts and an amazing place to stay! Would definitely come back
Guest favorite
Guesthouse in Fernandina Beach
4.94 out of 5 average rating, 62 reviews

Cord Grass Court

KimRating, 5 stars2 days ago
Very accurate photos! Bikes very handy! Take them to the beach and thru neighborhood with wild peacocks!! Truly amazing
Superhost
Guesthouse in Jacksonville
5 out of 5 average rating, 28 reviews

Studio Guesthouse near DT Jax/NAS, newly rehab!

ClaytonRating, 5 stars5 months ago
Stay was very pleasant as well as clean and organized.
Guest favorite
Guesthouse in Jacksonville
4.91 out of 5 average rating, 234 reviews

Large 1 bedroom Cottage with full kitchen

SemornRating, 5 stars1 week ago
It was a very beautiful home. It had everything we needed. Very quiet neighborhood. If I visit Jacksonville again I hope I am welcome back to the house.
Superhost
Guesthouse in Neptune Beach
5 out of 5 average rating, 4 reviews

Be A Nomad | Lovely Neptune Beach 2bed, monthly

ChristianaRating, 5 stars2 months ago
200 Cherry was a perfect home away from home. We loved the location to the ocean and to Atlantic Beach's restaurants. The kitchen had all the necessities and was clean and tidy. The home was nicely decorated and comfortable. The hosts were friendly and accommodating and thoughtful too. We look forward to booking with Nomad again.
Top guest favorite
Guesthouse in Jacksonville
4.94 out of 5 average rating, 51 reviews

Serene Getaway at Casa Blanca

JaniyahRating, 5 stars6 days ago
Upon arriving at the location, we noticed that the neighborhood was very peaceful and cleanly! It smelled amazing when we first walked in, and everything looked freshly cleaned. The decor creates a serene atmosphere, making it easy to relax and unwind. I totally recommend staying here…10/10 experience!

Destinations to explore