Guesthouse vacation rentals in Jefferson County

Find and book unique guesthouse rentals on Airbnb

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Popular amenities for Jefferson County guesthouse rentals

Family-friendly guest house rentals

Guest favorite
Guesthouse in Louisville
4.95 out of 5 average rating, 64 reviews

Retro Chic Private Getaway in the Highlands.

RachelRating, 5 stars4 months ago
Stacy was so friendly and helpful and took measurements of the space to make sure my wheelchair would fit. Great first floor stay with space for smaller manual wheelchairs! Would definitely stay again.
Top guest favorite
Guesthouse in Louisville
4.94 out of 5 average rating, 70 reviews

Yoga Barn with 90’s Loft Bedroom

BillRating, 5 stars3 days ago
Our stay at Anne’s place was absolutely perfect! The home was spotless, comfortable, and had everything we needed. Anne was incredibly responsive and helpful throughout our stay, making everything seamless. The location was fantastic—easy to access and close to great restaurants, bars, and activities. We couldn’t have asked for a better experience. Thank you, Anne!
Guest favorite
Guesthouse in Pendleton
4.89 out of 5 average rating, 64 reviews

The Waterfall Place, Suite and Walkout!

BrianaRating, 5 stars2 weeks ago
This place is a slice of heaven. It’s quiet and perfect for a group of family / family friends / and for myself a bachelorette group. We enjoyed the tranquility and the feeling of right at home! The house was cute and clean. You get your bang for your buck here. My only advice would be if you book, bring a car that can climb a hill, as the home is on top of (what feels like) mountain! But makes for gorgeous views.
Top guest favorite
Guesthouse in Shepherdsville
4.96 out of 5 average rating, 52 reviews

Bourbon Country/ Derby Guest House

MelanieRating, 5 stars8 months ago
Ramona and Steve were fantastic hosts. They made us feel right at home. Their location is beautiful and peaceful and just good for the soul! If my family and I are ever in the area again we will definitely love to visit again!
Guest favorite
Guesthouse in Louisville
4.92 out of 5 average rating, 296 reviews

Charming Carriage House with 2 private baths.

JuliannRating, 5 stars6 months ago
Perfect place to stay for a family of 4. Private and short drive from everything. Very clean.

Guest house rentals with a patio

Guest favorite
Guesthouse in Louisville
4.9 out of 5 average rating, 21 reviews

Cute &Cozy Carriage Home - Kentucky Derby Special!

HollisRating, 5 stars2 days ago
Maria’s place is so quiet and relaxing. It was just the spot that my dog & I needed for a couple of days to rest.
Top guest favorite
Guesthouse in Bloomfield
5 out of 5 average rating, 9 reviews

Country 1 bedroom guesthouse with heated pool

EmilyRating, 5 stars6 months ago
Valerie, Jim, and Dixie were absolutely fantastic! I can’t say enough good things about them and their lovely home. I felt so welcomed and had the best time. Valerie was especially personable and me feel comfortable and right at home. She gave me a few lifts to Bardstown, which were beyond helpful and shared some great recommendations! The pool and fishing pond are delightful, the hammock is amazing, and the views are beautiful. Angel’s Rest was pure paradise and I would 100% stay again!!
Guesthouse in Crestwood
5 out of 5 average rating, 3 reviews

Lots of cozy and fun space!

MarcRating, 5 stars6 months ago
Stephanie was incredible! She was super kind, welcoming, and accommodating, especially when we had an issue with another place we had planned on staying. She let us check in early and let us add another night last minute. The space was lovely! Very clean and homey. Plenty to do indoors, had all the amenities listed, and the surrounding area was beautiful. Whole heartedly recommend staying here! Stephanie is awesome and the space is awesome!
Top guest favorite
Guesthouse in Louisville
5 out of 5 average rating, 41 reviews

2BR Sterling Springs Guest Suite

BennyRating, 5 stars1 month ago
Outstanding stay. In just one word: PERFECT! My second time at Emily's, exactly one year apart, there's a reason why I'm back. Place is gorgeous, just as described, beautiful and peaceful neighborhood, close enough from the action but far enough and incredibly calming and relaxing. Lots of dining and shopping options right on Shelbyville Rd for the immediate needs. Very well located to access downtown Louisville or head out to Bardstown, Frankfort or Lexington. Emily is incredibly kind and truly focused on her guests having a great experience. Recommended with 6 stars in a heartbeat. Certainly it will be my very first option on my next Louisville adventure.
Top guest favorite
Guesthouse in Jeffersonville
4.9 out of 5 average rating, 67 reviews

Modern Guesthouse overlooking Ohio River

StanislavRating, 5 stars5 days ago
Amazing clean and private apartment. Hosts are very helpful and accommodating. Also one of the best valued for the price paid properties in the area.
Guest favorite
Guesthouse in Louisville
4.95 out of 5 average rating, 19 reviews

The tiny Walnut in Beechmont

TimRating, 5 stars6 months ago
Adam's place was comfortable & he was quick to respond to questions & resolve issues.
Guest favorite
Guesthouse in Louisville
4.9 out of 5 average rating, 83 reviews

Chic Derby stay minutes from Churchill Downs!

CraigRating, 5 stars1 month ago
Lauren was very accommodating and very helpful. She went above and beyond to make our stay great! Highly recommend and would stay again if I needed a place in the Louisville area. House was clean and looked just like the photographs!
Guesthouse in Louisville
4.67 out of 5 average rating, 12 reviews

Cozy & fun Studio Near Churchill Downs/Fairgrounds

AshleeRating, 5 stars3 days ago
hosts are super friendly and helped with anything that we needed. everything was super clean and I loved sitting on the back porch at night and first thing in the morning. they also had everything you could need in kitchen and bathroom. I do plan to stay again when I come back to town. I had a really great time and very relaxing.

Guest house rentals with a washer and dryer

Guest favorite
Guesthouse in Louisville
4.98 out of 5 average rating, 85 reviews

Highlands Carriage House - Deer Park

LynnRating, 5 stars3 months ago
We had a great stay. The apartment was clean, the bed was comfortable, and the kitchen was well-equipped. We enjoyed the cute neighborhood and walked to dinner at good restaurants every night. Kellie went out of her way to help us and was a great host!
Top guest favorite
Guesthouse in Louisville
5 out of 5 average rating, 53 reviews

New custom guesthouse | Free parking | Sleeps 4

LilyRating, 5 stars2 weeks ago
This was a wonderful location for us. It was just the right size, very comfortable and had everything we needed to be able to cook a few meals if we wanted. We were also very impressed with some of the thoughtful details like the pretty flowers in the living room or letting us know we could switch from heat to AC when the weather changed mid-week during our stay. Skylar is a superhost and very responsive. We highly recommend!!
Top guest favorite
Private room in Prospect
5 out of 5 average rating, 11 reviews

Lewis & Clark Trail Guest Suite

RobertRating, 5 stars1 month ago
If I could i’d give Deborah more than 5 ⭐️ She was an amazing host and took extra time to set the room up specially for Valentine’s day. She went out of her way to make our stay the best experience we have had on AirBnb. She recommended lots of restaurants and the one we decided to go to might have had the best seafood i’ve ever had. She also sent me many trails where I could run at and was super informative on everything she recommended! The place was beautiful and it felt like a home and this is definitely some place i’d love to come back to! Thanks again Deborah!
Superhost
Guesthouse in Jeffersonville
5 out of 5 average rating, 4 reviews

DeaconessGuesthouseUnit2~Hot Tub~Pet~Lux Amenities

KellyRating, 5 stars6 months ago
Fantastic hosts, the air bnb was exactly as described, a beautiful location close to many things in Nulu, The Highlands and Downtown. Very accommodating hosts and very easy to communicate with! I highly recommend this spot!
Guest favorite
Guesthouse in Louisville
5 out of 5 average rating, 7 reviews

Private 3BR luxury apartment

SuzanneRating, 5 stars4 months ago
We enjoyed our stay at Juan’s place for a Thanksgiving weekend. Beds were comfy and the kitchen was well- equipped as we made some dishes to take to the family feast. Didn’t have opportunity to do much in the area as it was a holiday, but there are some fun places nearby. Next time!
Top guest favorite
Guesthouse in Louisville
5 out of 5 average rating, 71 reviews

Lavish church suite with choir loft

MollyRating, 5 stars1 week ago
This Airbnb is perfect! The decor is incredible and it’s walkable to so much. The place was very clean and I really appreciated the hosts recommendations and great communication about checking in and out. I’d absolutely stay here again!

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