Guesthouse vacation rentals in Jefferson County

Find and book unique guesthouse rentals on Airbnb

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Popular amenities for Jefferson County guesthouse rentals

Family-friendly guest house rentals

Guest favorite
A modern living area features a pink sectional sofa adorned with blue and orange throw pillows. A decorative wall art piece and a round mirror provide a vibrant focal point against a chevron-patterned accent wall. Soft lighting emanates from a stylish light fixture overhead.
Guesthouse in Louisville
4.95 out of 5 average rating, 64 reviews

Retro Chic Private Getaway in the Highlands.

RachelRating, 5 stars4 months ago
Stacy was so friendly and helpful and took measurements of the space to make sure my wheelchair would fit. Great first floor stay with space for smaller manual wheelchairs! Would definitely stay again.
Guest favorite
A compact kitchenette features stylish elements such as a patterned backsplash and a window allowing natural light. Two green bar stools are positioned at the counter, while a small sink and microwave are visible. A potted plant adds a touch of greenery to the space.
Guesthouse in Louisville
4.93 out of 5 average rating, 72 reviews

Yoga Barn with 90’s Loft Bedroom

BillRating, 5 stars3 weeks ago
Our stay at Anne’s place was absolutely perfect! The home was spotless, comfortable, and had everything we needed. Anne was incredibly responsive and helpful throughout our stay, making everything seamless. The location was fantastic—easy to access and close to great restaurants, bars, and activities. We couldn’t have asked for a better experience. Thank you, Anne!
Guest favorite
Guesthouse in Pendleton
4.89 out of 5 average rating, 65 reviews

The Waterfall Place, Suite and Walkout!

BrianaRating, 5 stars1 month ago
This place is a slice of heaven. It’s quiet and perfect for a group of family / family friends / and for myself a bachelorette group. We enjoyed the tranquility and the feeling of right at home! The house was cute and clean. You get your bang for your buck here. My only advice would be if you book, bring a car that can climb a hill, as the home is on top of (what feels like) mountain! But makes for gorgeous views.
Top guest favorite
A view from the guest house porch reveals a serene pasture with several horses grazing. A black wooden fence encircles the expansive, green field under a clear blue sky, creating a peaceful rural atmosphere. The surrounding trees provide a natural backdrop.
Guesthouse in Shepherdsville
4.96 out of 5 average rating, 52 reviews

Bourbon Country/ Derby Guest House

MelanieRating, 5 stars9 months ago
Ramona and Steve were fantastic hosts. They made us feel right at home. Their location is beautiful and peaceful and just good for the soul! If my family and I are ever in the area again we will definitely love to visit again!
Guest favorite
Guesthouse in Louisville
4.92 out of 5 average rating, 297 reviews

Charming Carriage House with 2 private baths.

JeanneRating, 5 stars2 weeks ago
This was my 2nd time to stay at Stacy's place. It was just as clean and accommodating as I remembered it! Stacy's place is located in a trendy neighborhood with international dining options. Louisville is a short 15 minutes away. I recommend visiting the zoo, which is just 5 minutes from the rental. Neighborhood is extremely safe and dog friendly. I couldn't recommend this place more!

Guest house rentals with a patio

Guesthouse in Louisville
4.83 out of 5 average rating, 23 reviews

Less than 20 min to Churchill - KY Derby-Sleeps 4!

AshleyRating, 5 stars3 weeks ago
Lots of space, plenty of games, open concept and clean. Close to town but on a secluded property which was really refreshing. Host was super responsive and made our stay worthwhile.
Top guest favorite
A green lawn surrounds a fenced-in area featuring a heated pool, with lush banana plants adding to the tropical feel. The house, painted in muted tones, is visible in the background, with outdoor seating areas nearby, inviting relaxation.
Guesthouse in Bloomfield
5 out of 5 average rating, 9 reviews

Country 1 bedroom guesthouse with heated pool

EmilyRating, 5 stars7 months ago
Valerie, Jim, and Dixie were absolutely fantastic! I can’t say enough good things about them and their lovely home. I felt so welcomed and had the best time. Valerie was especially personable and me feel comfortable and right at home. She gave me a few lifts to Bardstown, which were beyond helpful and shared some great recommendations! The pool and fishing pond are delightful, the hammock is amazing, and the views are beautiful. Angel’s Rest was pure paradise and I would 100% stay again!!
A spacious living area features a combination of seating options, including a couch and armchair with decorative pillows. A coffee table sits in the center, while the open layout leads to a dining area and fully equipped kitchen in the background.
Guesthouse in Crestwood
5 out of 5 average rating, 3 reviews

Lots of cozy and fun space!

MarcRating, 5 stars6 months ago
Stephanie was incredible! She was super kind, welcoming, and accommodating, especially when we had an issue with another place we had planned on staying. She let us check in early and let us add another night last minute. The space was lovely! Very clean and homey. Plenty to do indoors, had all the amenities listed, and the surrounding area was beautiful. Whole heartedly recommend staying here! Stephanie is awesome and the space is awesome!
Top guest favorite
A bright living area features a light blue couch and a black futon, providing additional seating options. A wooden coffee table is centrally placed on a patterned rug. Natural light enters through a glass door leading to the outside, with minimalistic decor enhancing the space.
Guesthouse in Jeffersonville
4.9 out of 5 average rating, 68 reviews

Modern Guesthouse overlooking Ohio River

StanislavRating, 5 stars3 weeks ago
Amazing clean and private apartment. Hosts are very helpful and accommodating. Also one of the best valued for the price paid properties in the area.
Guest favorite
A studio space is shown with warm wood-like flooring, featuring a full bed dressed in a green blanket. An air conditioning unit is positioned near a window, and a flat-screen TV is mounted on the wall opposite the bed. A floor lamp and a small table complete the room.
Guesthouse in Louisville
4.95 out of 5 average rating, 20 reviews

The tiny Walnut in Beechmont

JoshRating, 5 stars1 week ago
Very convenient to the Expo Center... More comfortable than a chain hotel room. Would certainly use again if the price made sense.
Guest favorite
An open concept living area presents a spacious layout with a red leather sofa and two black chairs surrounding a circular coffee table. A large Smart TV is mounted on the wall, and the area leads to a fully equipped kitchen, while natural light fills the space.
Guesthouse in Louisville
4.9 out of 5 average rating, 83 reviews

Chic Derby stay minutes from Churchill Downs!

CraigRating, 5 stars1 month ago
Lauren was very accommodating and very helpful. She went above and beyond to make our stay great! Highly recommend and would stay again if I needed a place in the Louisville area. House was clean and looked just like the photographs!
A vibrant mural of horse racing creates a dynamic focal point on the wall of the cozy sleeping area. A spacious bed with blue bedding sits opposite a wall-mounted television, complemented by a small table on one side, enhancing the room's charm.
Guesthouse in Louisville
4.62 out of 5 average rating, 13 reviews

Cozy & fun Studio Near Churchill Downs/Fairgrounds

AshleeRating, 5 stars3 weeks ago
hosts are super friendly and helped with anything that we needed. everything was super clean and I loved sitting on the back porch at night and first thing in the morning. they also had everything you could need in kitchen and bathroom. I do plan to stay again when I come back to town. I had a really great time and very relaxing.
A cozy seating area is highlighted by a soft blue couch adorned with light pillows. A mid-century modern coffee table sits in front, displaying a simple white candle. A prominent brick wall features artwork referencing the Louisville Carriage House, complemented by an air conditioning unit and a bedside table.
Guesthouse in Louisville
New place to stay

New | Custom & Creative Space | Walk to Top Shops

MadisonRating, 5 stars4 weeks ago
I can’t say enough great things about this carriage house and the amazing hospitality of Christina and Shane! From the moment I arrived, it was clear that every detail had been thoughtfully selected to create a welcoming and comfortable stay. The space itself is absolutely gorgeous—open and bright with plenty of natural light and equipped with automatic blackout shades for the perfect night's sleep. Everything was impeccably clean, and the high-end appliances (including a great coffee maker, washer, and dryer) made it feel like a true home away from home. The kitchen was impressively stocked with cookware, utensils, and a variety of seasonings, making it easy to prepare meals. I especially loved the thoughtful touches that gave the space a unique Kentucky charm! This is hands-down one of the best Airbnb stays I’ve had, and I highly recommend it!

Guest house rentals with a washer and dryer

Guest favorite
A modern kitchen area is visible, featuring white cabinetry and stainless steel appliances. A large island with seating for four stands at the center. Light from multiple windows illuminates the space, complemented by decorative greenery atop the cabinetry.
Guesthouse in Louisville
4.98 out of 5 average rating, 86 reviews

Highlands Carriage House - Deer Park

RyanRating, 5 stars1 week ago
Awesome spot. Very private. Very walkable area close to some great bars, restaurants, coffee shops, local shops, and a cat cafe. The unit itself was spacious, very clean, and has everything you could need including a washer and dryer which we needed unexpectedly. The bed was really comfortable as were the linens. Kellie was a great host and is super fast in responses, and checked in on us to make sure we didn’t have any issues. I would love to stay here again in a future trip to Louisville.
Top guest favorite
The entrance features a wooden staircase leading to a black door, framed by natural wood siding. A small potted plant adorns the porch, while trees in vibrant autumnal colors are visible in the background, contributing to a welcoming entryway.
Guesthouse in Louisville
5 out of 5 average rating, 54 reviews

New custom guesthouse | Free parking | Sleeps 4

BenjaminRating, 5 stars1 week ago
The property was very convenient and in a great part of the city to access restaurants and small shops. It was also private and made the trip very relaxing. The home is extremely comfortable and stylish.
Top guest favorite
A modern kitchen is equipped with stainless steel appliances, including a refrigerator and oven. White cabinets provide ample storage, while a patterned rug adds warmth to the space. Natural light filters through a window above the sink, enhancing the functional layout.
Private room in Prospect
5 out of 5 average rating, 11 reviews

Lewis & Clark Trail Guest Suite

RobertRating, 5 stars2 months ago
If I could i’d give Deborah more than 5 ⭐️ She was an amazing host and took extra time to set the room up specially for Valentine’s day. She went out of her way to make our stay the best experience we have had on AirBnb. She recommended lots of restaurants and the one we decided to go to might have had the best seafood i’ve ever had. She also sent me many trails where I could run at and was super informative on everything she recommended! The place was beautiful and it felt like a home and this is definitely some place i’d love to come back to! Thanks again Deborah!
Top guest favorite
A spacious living area showcases a contemporary design with a grey sectional sofa and vibrant yellow accent pillow. Natural light brightens the space, highlighting a round dining table surrounded by upholstered chairs. A stylish spiral staircase connects the two levels, and a charming chandelier hangs from the ceiling.
Guesthouse in Louisville
5 out of 5 average rating, 73 reviews

Lavish church suite with choir loft

JonathanRating, 5 stars3 weeks ago
The space is incredible, with fantastic furnishing, tile, wallpaper, massive windows, and a triple-height space with beautiful wood trusses. The kitchen was great, and the dining banquet was so nice that my wife now wants one. The attention to detail, like the record player, variety of glassware, and cabinet staples, made our stay feel like we were staying in a home and not a rental unit. The neighborhood is excellent, with restaurants, shops, liquor stores, and markets all within a block three-block radius. Even Whiskey Row is less than a mile away, with three distilleries within a two-block walk. I can't imagine a better place to stay if you consider visiting downtown Louisville.
Superhost
A spacious outdoor deck overlooks the river, featuring a round wooden table set with a platter of fresh fruit and drinks. Comfortable seating is arranged nearby, and a detailed railing frames the scene against a backdrop of the river and a distant bridge.
Guesthouse in Jeffersonville
5 out of 5 average rating, 3 reviews

DeaconessGuesthouseUnit4'Pets'Firepit'Waterfront

SherryRating, 5 stars9 months ago
We’ve stayed in lots of Airbnb’s over the years but I have to say this tops them all. Beautiful house, very comfortable and inviting. The owner responded every time very quickly. The backyard, the front porch and the upper deck are perfect for hanging out with friends or enjoying the peacefulness of the river. Can’t wait to book this place again.
Guesthouse in Louisville
5 out of 5 average rating, 155 reviews

Your Derby Weekend Getaway

JaneRating, 5 stars28 months ago
Stayed here for two months and wish I could've stayed longer! Perfect amount of space to live and work. Very clean, lots of light, stocked with all the essentials, comfortable bed. The location is in walking distance of a few restaurants and entertainment. A quick drive (or bike ride) to the riverfront and NuLu. The small fenced in courtyard was really convenient to let my dog out. Joan was a great host, very friendly and accommodating.

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